Abstract (eng)
Atrial fibrillation is the most commonly encountered arrhythmia in clinical practice. It is
associated with substantial morbidity and mortality. Prevalence of this disorder increases
with age, rising above 5% in people older than 65, affecting about 6 million worldwide. It
therefore represents a growing clinical and economic burden.
Formerly considered a benign disorder, atrial fibrillation can have serious clinical
consequences. The risk of thromboembolic stroke increases 5-fold, cardiac output
decreases whereas the strain on the heart increases, and with it the risk of developing
serious chronic heart conditions, including dilated cardiomyopathy and congestive heart
failure.
This study included 6593 patients who underwent a rehabilitation program in the
rehabilitation centre of Bad Schallerbach during the years 2000 – 2005. Of these patients,
302 represented themselves with atrial fibrillation.
In this study, a significant correlation between atrial fibrillation, the appearance of chronic
heart disease and hypertonia can be reported.
The arrhythmia itself cannot be associated with the presence of diabetes mellitus. A
relation to a shunt procedure can be excluded as well.
At the end of their rehabilitation program, patients with atrial fibrillation showed
significant changes concerning their cholesterol-, LDL-, CRP- and FBG-parameters. The
difference of change, compared to the parameters of those patients without the arrhythmia
was also of significance.
Significant differences could be observed between patients with and without atrial
fibrillation, as far as their maximum O2 uptake is concerned. Interestingly patients with
arrhythmia showed a lower absolute maximum O2 uptake, whereas their relative O2 uptake
was higher.
-132-
This study showed no influence of left atrial size in regard to cholesterol-, LDL-, CRP-,
and FBG-parameters or the levels of TSH and the glomerular filtration rate.