The Microsoft Excel table shows the off-target interaction profile of marketed drugs in Austria. The compounds are listed as rows and the off-targets are displayed as columns.
The interaction data set was extracted from the Chembl database.
The blue color shading indicates an interaction between the off-target and the active substance: The darker the blue color, the stronger the interaction. The strength of the interaction was assessed using the pChEMBL value. The pChEMBL value is the negative decadic logarithm of the concentration of an active substance required to achieve a certain biological activity. A high pChEMBL value means a higher activity of the active substance.
In addition, the red color indicates, that the interaction was found in other databases beside ChEMBL.