Abstract (eng)
The aim of this study was to determine antimicrobial effect of dermal applied oregano essential oil in the urine. The study was conducted in collaboration between the Department of Clinical Pharmacy and Diagnostics at the University of Vienna and practice Dr. Dorfinger.
Patients were ad hoc selected when they were examined by urologist and divided equally into one of 3 independent groups. Group 1 was treated one week with an oregano nursing oil (5% in jojoba oil) and ibuprofen, group 2 with oregano nursing oil and an antibiotic and group 3 with pure jojoba oil and an antibiotic. Between the first day (day of examination) and Day 8 (Day of control) treatment was carried out. During these 7 days information about patients, symptoms and etc., were collected and urine was taken for bacteriological analysis. The statistical analysis of the data collected from these three groups was performed with Variance analysis (ANOVA) and t-Test.
There was no significant difference in the number of germs and leucocytes between the treatment methods. The number of bacteria and leukocyte decreased directly proportional in all three groups from day 1 to day 8. Likewise, the number of erythrocytes and the proteins in the urine did not differ significantly. In terms of subjective symptoms, neither significant difference nor a trend was determined. All patients felt better at the end of therapy.
Both oregano oil groups described the scent of nursing oil as more intensive and as more known, unlike patients from jojoba oil group. The hedonics evaluation of groups 1 and 2 showed no significance while intensity showed one trend. The patients from group 1 and 2 have described the scent of oregano oil more or less as known, unlike patients from Group 3, which described the scent of jojoba oil as unknown and odorless. Regarding the subjective experience of oil scent, the whole collective described the oil scent as soothing and entire treatment as very pleasant.