A curated dataset of modern and ancient high-coverage shotgun human genomes

Pierpaolo Maisano Delser; Eppie R. Jones; Anahit Hovhannisyan; Lara Cassidy; Ron Pinhasi; Andrea Manica

doi:10.1038/s41597-021-00980-1

Titel

A curated dataset of modern and ancient high-coverage shotgun human genomes

Autor*in

Pierpaolo Maisano Delser

Department of Zoology, University of Cambridge

Eppie R. Jones

Department of Zoology, University of Cambridge

Anahit Hovhannisyan

Institute of Molecular Biology, National Academy of Sciences, Armenia

... show all

Abstract

Over the last few years, genome-wide data for a large number of ancient human samples have been collected. Whilst datasets of captured SNPs have been collated, high coverage shotgun genomes (which are relatively few but allow certain types of analyses not possible with ascertained captured SNPs) have to be reprocessed by individual groups from raw reads. This task is computationally intensive. Here, we release a dataset including 35 whole-genome sequenced samples, previously published and distributed worldwide, together with the genetic pipeline used to process them. The dataset contains 72,041,355 sites called across 19 ancient and 16 modern individuals and includes sequence data from four previously published ancient samples which we sequenced to higher coverage (10–18x). Such a resource will allow researchers to analyse their new samples with the same genetic pipeline and directly compare them to the reference dataset without re-processing published samples. Moreover, this dataset can be easily expanded to increase the sample distribution both across time and space. Measurement(s) genome Technology Type(s) DNA sequencing Factor Type(s) modern/ancient human Sample Characteristic - Organism Homo sapiens Machine-accessible metadata file describing the reported data: doi.org/10.6084/m9.figshare.14839329

Stichwort

Genetic variationPopulation genetics

Objekt-Typ

journal article

Sprache

Englisch [eng]

Persistent identifier

phaidra.univie.ac.at/o:1603844

DOI

10.1038/s41597-021-00980-1

Erschienen in

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