Titel
Quantitative Analysis of Core Lipid Production in Methanothermobacter marburgensis at Different Scales
Autor*in
Lydia M. F. Baumann
Institute for Geology, Center for Earth System Research and Sustainability, Universität Hamburg
Autor*in
Kinga Oláh
Institute for Synthetic Bioarchitectures, Department of Nanobiotechnology, University of Natural Resources and Life Sciences
... show all
Abstract
Archaeal lipids have a high biotechnological potential, caused by their high resistance to oxidative stress, extreme pH values and temperatures, as well as their ability to withstand phospholipases. Further, methanogens, a specific group of archaea, are already well-established in the field of biotechnology because of their ability to use carbon dioxide and molecular hydrogen or organic substrates. In this study, we show the potential of the model organism Methanothermobacter marburgensis to act both as a carbon dioxide based biological methane producer and as a potential supplier of archaeal lipids. Different cultivation settings were tested to gain an insight into the optimal conditions to produce specific core lipids. The study shows that up-scaling at a constant particle number (n/n = const.) seems to be a promising approach. Further optimizations regarding the length and number of the incubation periods and the ratio of the interaction area to the total liquid volume are necessary for scaling these settings for industrial purposes.
Stichwort
archaea biotechnologymicrobial physiologyanaerobeisoprenoidsether lipidsmethanogens
Objekt-Typ
Sprache
Englisch [eng]
Persistent identifier
Erschienen in
Titel
Bioengineering
Band
9
Ausgabe
4
ISSN
2306-5354
Erscheinungsdatum
2022
Publication
MDPI AG
Projekt
Kod / Identifikator
859293
Projekt
Kod / Identifikator
P 29399-B22
Erscheinungsdatum
2022
Zugänglichkeit
Rechteangabe
© 2022 by the authors

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