Titel
Engineered yeasts and lignocellulosic biomaterials: shaping a new dimension for biorefinery and global bioeconomy
Autor*in
Tunde Sheriffdeen Bello
Department of Plant Biology, School of Life Sciences, Federal University of Technology Minna
Autor*in
Peter Olusakin Oladoye
Department of Chemistry and Biochemistry, Florida International University
... show all
Abstract
The next milestone of synthetic biology research relies on the development of customized microbes for specific industrial purposes. Metabolic pathways of an organism, for example, depict its chemical repertoire and its genetic makeup. If genes controlling such pathways can be identified, scientists can decide to enhance or rewrite them for different purposes depending on the organism and the desired metabolites. The lignocellulosic biorefinery has achieved good progress over the past few years with potential impact on global bioeconomy. This principle aims to produce different bio-based products like biochemical(s) or biofuel(s) from plant biomass under microbial actions. Meanwhile, yeasts have proven very useful for different biotechnological applications. Hence, their potentials in genetic/metabolic engineering can be fully explored for lignocellulosic biorefineries. For instance, the secretion of enzymes above the natural limit (aided by genetic engineering) would speed-up the down-line processes in lignocellulosic biorefineries and the cost. Thus, the next milestone would greatly require the development of synthetic yeasts with much more efficient metabolic capacities to achieve basic requirements for particular biorefinery. This review gave comprehensive overview of lignocellulosic biomaterials and their importance in bioeconomy. Many researchers have demonstrated the engineering of several ligninolytic enzymes in heterologous yeast hosts. However, there are still many factors needing to be well understood like the secretion time, titter value, thermal stability, pH tolerance, and reactivity of the recombinant enzymes. Here, we give a detailed account of the potentials of engineered yeasts being discussed, as well as the constraints associated with their development and applications.
Stichwort
Bioengineeringsynthetic yeastsmetabolic pathwaysbiorefineriesbioeconomylignocellulosic materials
Objekt-Typ
Sprache
Englisch [eng]
Persistent identifier
https://phaidra.univie.ac.at/o:2069159
Erschienen in
Titel
Bioengineered
Band
14
Ausgabe
1
ISSN
2165-5979
Erscheinungsdatum
2023
Verlag
Informa UK Limited
Projektnummer
MPC-2021-00421 – Österreichischer Austauschdienst (OeAD)
Erscheinungsdatum
2023
Zugänglichkeit
Rechteangabe
© 2023 The Author(s)

Herunterladen

Universität Wien | Universitätsring 1 | 1010 Wien | T +43-1-4277-0