Screening for multicopy suppressors of a yeast mrs3/4Δ mutant : an attempt to discover novel mitochondrial iron transporters

Markus Binder

doi:10.25365/thesis.4250

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Title (eng)

Screening for multicopy suppressors of a yeast mrs3/4Δ mutant

an attempt to discover novel mitochondrial iron transporters

Parallel title (deu)

Screening nach Suppressoren einer mrs3/4Δ Mutante ; ein Versuch, mitochondriale Eisentransporter zu entdecken

Author

Markus Binder

Adviser

Rudolf Schweyen

Assessor

Andreas Hartig

Abstract (deu)

Es wurde ein genetischer Screen durchgeführt, um Suppressoren einer mrs3/4Δ Mutante (und somit mitochondriale Eisentransporter) zu finden. Leider wurden keine Eisentransporter gefunden, aber es konnte belegt werden, dass der Pyrimidintransporter RIM2 (MRS12) Eisen transportieren kann.

Abstract (eng)

A genetic screen was carried out to find suppressors of a yeast mrs3/4Δ mutant and therefore to reaveal novel mitochondrial iron transporters. Unfortunately no iron transporters were found, but it was demonstrated that the pyrimidine transporter RIM2 (MRS12) is able to transport iron.

Keywords (eng)

genetic screeningMRS3MRS4MRS12RIM2suppressioniron transportmitochondria

Keywords (deu)

Genetischer ScreenMRS3MRS4MRS12RIM2SuppressionEisentransportMitochondrien

Subject (deu)

Naturwissenschaften allgemein: Allgemeines

Subject (deu)

Molekularbiologie

Type (deu)

Diplomarbeit

Persistent identifier

https://phaidra.univie.ac.at/o:1255965